The type of inflammation caused by excess weight has been associated with numerous health risks, including development of type 2 diabetes and cardiovascular issues. Now, new research suggests there may be one risk you may not have considered: gum disease.

A study in the Journal of Dental Research found that excessive inflammation linked to obesity increased the amount of myeloid-derived suppressor cells, or MDSCs. These originate in bone marrow and develop into numerous cell types, including a kind called osteoclasts that break down bone tissue.

That’s an issue throughout the body, but can be particularly problematic in your mouth, the researchers note. That’s because bone holds your teeth in place, and when that foundation is weakened, it can lead to gum disease and potential tooth loss.

Related: This Is the Worst Food for Your Teeth, Dentist Says

“Previous research suggests there’s a clear relationship between obesity and gum disease and our study shows that might be due to higher amounts of osteoclasts,” says study co-author Keith Kirkwood, DDS, Ph.D., professor of oral biology at the University of Buffalo School of Dental Medicine.

Although the study examined two groups of mice—with one group fed a diet that caused fast weight gain and subsequent inflammation spikes—the results are likely similar in people since the mechanism is the same, says Kirkwood.

“This process would not only explain the connection between excess weight and gum disease, but may also shed light on mechanisms behind other inflammatory, bone-related diseases that tend to develop along with obesity,” he adds. That includes arthritis and osteoporosis.

Why does weight gain cause such a dramatic reaction? Some experts have noted that overeating can increase the immune response because the body is stressed by that level of consumption.

In response, the immune system generates excessive inflammation as a way to handle the threat. If you overeat occasionally, that’s not a big deal, because your inflammation will lower once the perceived stress has passed. But, regularly consuming high amounts, and gaining weight as a result, will make that inflammation chronic, and that’s when the health risks begin increasing.

“It’s a balancing act,” says Bente Halvorsen, Ph.D., professor at the Research Institute for Internal Medicine at the University of Oslo in Norway. “But we can reduce the inflammatory reaction by losing weight, or at least by being more conscious of the effects of gaining weight.”

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Several women say they wish they hadn’t tried weight-loss tea products that allegedly cost them their jobs.

Three women told a TV news station in Charlotte that they failed employer drug tests after consuming Total Life Change’s Iaso tea and subsequently testing positive for tetrahydrocannabinol, or THC for short. That’s the chemical in marijuana that makes you feel “high.”

WSOC-TV asked an independent lab to test two samples of the tea for THC. Though the front packaging stated that it had 0.0%, the results revealed trace levels of THC that were “potentially” enough for a failed drug test. “It took me well over a month and a half to pass an at-home drug test,” one user told the outlet. (RELATED: The One Vitamin Doctors Are Urging Everyone to Take Right Now)

The FDA says products containing “no more than 0.3% THC on a dry weight basis are no longer controlled substances under federal law,” which means the tea is legal. But that doesn’t explain why the packaging said there was no THC, and WSOC-TV has since unearthed three class-action lawsuits.

Total Life Changes has reportedly updated its packaging on the raspberry lemonade tea, which comes in regular and instant versions, to state that it does “not recommend use if you are subject to drug testing.”

“We are aware of the allegations about one of our tea products. At TLC, we care deeply about our customers and are committed to their well-being,” the company told WSOC-TV. “We are in the process of learning more about the relevant facts, but are not in a position to report more fully at this time.”

There are truly natural ways to stay well—check out the three fruits that drive weight loss the most. And to get all of the latest beverage news delivered straight to your email inbox every day, sign up for our newsletter!

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